Neurology and Neurosurgery
Contact
Prof Lakshmi Nagarajan | Paediatric Neurologist/ Epileptologist
Lakshmi.Nagarajan@health.wa.gov.au
Lakshmi.Nagarajan@health.wa.gov.au
Departmental Overview
The Children’s Neuroscience Service has a research program that spans a wide spectrum of neurological disorders. Areas of active research are Epilepsy (investigation and treatment), Non Invasive Brain stimulation, Neonatal Neurology, Neurophysiology, Neurogenetics, Neuromuscular and Neurometabolic Disorders.
Members of the department are recipients of several research grants. We are currently running several clinical trials and research studies. We have collaborative projects with other departments at Perth Children’s Hospital, The Kids Research Institute Australia, other Universities in Australia and internationally. We have a highly productive research program with several peer reviewed publications each year. We present our research in national and international conferences and have been Invited and Plenary speakers at these meetings. Members of our staff are on scientific and advisory committees in the hospital and professional organizations and societies.
Members of the department are recipients of several research grants. We are currently running several clinical trials and research studies. We have collaborative projects with other departments at Perth Children’s Hospital, The Kids Research Institute Australia, other Universities in Australia and internationally. We have a highly productive research program with several peer reviewed publications each year. We present our research in national and international conferences and have been Invited and Plenary speakers at these meetings. Members of our staff are on scientific and advisory committees in the hospital and professional organizations and societies.
Current research projects
- NS Pharma NS-065/NCNP-01-301 study “A Phase 3 Randomized, Double-blind, Placebo-controlled, Multi-center Study to Assess the Efficacy and Safety of Viltolarsen in Ambulant Boys with Duchenne Muscular Dystrophy (DMD)” (Led by Kava)
- The characterisation of Three Dimensional facial profiles of Children with Syndromes
- Using wearable technology to support health and wellbeing in young people with Duchenne muscular dystrophy (Led by Downs et al and Kava)
- Transcranial magnetic stimulation in children with Benign Focal Epilepsy of Childhood + BFEC spectrum (Led by Ghosh and Nagarajan)
- Transcranial Direct current Stimulation tDCS for Children and Adolescents with Refractory Epilepsy (Led by Ghosh and Nagarajan)
- Active Implementation of Australian Consensus Guidelines for the Effective Delivery of Clinical Services to Patients with Mitochondrial Disorders-collaborative project (Project Member M. Kava)
- Co-investigator: Taurine as a therapy for Duchenne Muscular Dystrophy (DMD), and Becker Muscular Dystrophy (BMD) (Led by Arthur and Kava)
- Understanding Brain maturation in premature babies: Use of standard V-EEG to study electrical activity of the brain and neonatal seizures and predict neurodevelopmental outcome (Led by Ghosh, Nagarajan and Palumbo)
- VEEG vs aEEG study in Neonates (Led by Nagarajan, Ghosh, Palumbo and Neonatology Dept.)
- Intra-operative Neurophysiology Monitoring INM (Led by Ghosh, Nagarajan and Palumbo)
- Neonatal Neurophysiology and Neurology Led by Nagarajan, Ghosh, Palumbo and Neonatology Dept.)
- A multi-centre open label extension study to investigate safety and efficacy of Lacosamide as adjuvant therapy in Paediatric subjects with partial onset seizures (Led by Nagarajan, Walsh and Shah)
- New Onset Seizure Clinic (Led by Nagarajan, Walsh and Shah)
- Comprehensive Outcomes Registry in Patients with refractory epilepsy treated with Vagal Nerve Stimulation Therapy (Led by Nagarajan, Ghosh and Shah)
- IVIG therapy in children with Refractory Epilepsy (Led by Nagarajan and Ghia)
- Gastrostomy and Neurodevelopmental Disability (Led by Nagarajan, Forbes, Downs and Leonard (TKI)
- One of the chief investigators for PMH/PCH for project titled “ Establishment of an Australian Mitochondrial Disease Registry” and “Mitochondrial diseases –diagnostic pathway” study funded by Australian Genomics Health Alliance (Led by Kava).
Last Updated:
28/10/2024